Physical Properties | | | |
Molecular Weight: 405.733 g/mol | logS: -5.3719 | SlogP: 4.1577 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.207399 | Sterimol/B1: 2.539 | Sterimol/B2: 4.04746 | Sterimol/B3: 5.80545 |
Sterimol/B4: 6.16643 | Sterimol/L: 14.2595 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 583.82 | Positive charged surface: 238.36 | Negative charged surface: 345.46 | Volume: 328.375 |
Hydrophobic surface: 514.57 | Hydrophilic surface: 69.25 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |