Physical Properties | | | |
Molecular Weight: 386.408 g/mol | logS: -4.08662 | SlogP: 2.38672 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0865697 | Sterimol/B1: 3.7942 | Sterimol/B2: 4.68253 | Sterimol/B3: 5.50364 |
Sterimol/B4: 8.89808 | Sterimol/L: 17.7976 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 682.901 | Positive charged surface: 393.249 | Negative charged surface: 289.652 | Volume: 356.375 |
Hydrophobic surface: 453.919 | Hydrophilic surface: 228.982 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |