Physical Properties | | | |
Molecular Weight: 417.513 g/mol | logS: -4.88198 | SlogP: 3.08517 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0316522 | Sterimol/B1: 3.02278 | Sterimol/B2: 4.22897 | Sterimol/B3: 4.97718 |
Sterimol/B4: 10.6929 | Sterimol/L: 17.9394 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 737.925 | Positive charged surface: 533.43 | Negative charged surface: 198.824 | Volume: 411.75 |
Hydrophobic surface: 637.132 | Hydrophilic surface: 100.793 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |