Physical Properties | | | |
Molecular Weight: 397.479 g/mol | logS: -3.23336 | SlogP: 2.0564 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0846698 | Sterimol/B1: 2.31622 | Sterimol/B2: 2.4895 | Sterimol/B3: 6.99331 |
Sterimol/B4: 8.44521 | Sterimol/L: 18.8187 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 689.277 | Positive charged surface: 542.001 | Negative charged surface: 147.276 | Volume: 382.125 |
Hydrophobic surface: 571.683 | Hydrophilic surface: 117.594 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |