Physical Properties | | | |
Molecular Weight: 385.508 g/mol | logS: -5.51453 | SlogP: 4.09702 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0411469 | Sterimol/B1: 3.80476 | Sterimol/B2: 3.93287 | Sterimol/B3: 5.08545 |
Sterimol/B4: 5.8811 | Sterimol/L: 17.1781 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 621.818 | Positive charged surface: 318.808 | Negative charged surface: 303.01 | Volume: 351.375 |
Hydrophobic surface: 544.853 | Hydrophilic surface: 76.965 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |