Physical Properties | | | |
Molecular Weight: 381.819 g/mol | logS: -4.80775 | SlogP: 2.9257 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0243503 | Sterimol/B1: 2.40409 | Sterimol/B2: 2.65564 | Sterimol/B3: 3.63867 |
Sterimol/B4: 5.73491 | Sterimol/L: 21.5974 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 626.263 | Positive charged surface: 309.83 | Negative charged surface: 310.59 | Volume: 339.125 |
Hydrophobic surface: 475.686 | Hydrophilic surface: 150.577 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |