Physical Properties | | | |
Molecular Weight: 398.511 g/mol | logS: -5.30021 | SlogP: 4.15034 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0118441 | Sterimol/B1: 2.4568 | Sterimol/B2: 2.49835 | Sterimol/B3: 3.5328 |
Sterimol/B4: 6.74767 | Sterimol/L: 22.2036 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 676.639 | Positive charged surface: 368.31 | Negative charged surface: 308.329 | Volume: 359 |
Hydrophobic surface: 516.141 | Hydrophilic surface: 160.498 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |