Physical Properties | | | |
Molecular Weight: 403.437 g/mol | logS: -6.81791 | SlogP: 3.8451 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0118999 | Sterimol/B1: 2.4272 | Sterimol/B2: 2.65181 | Sterimol/B3: 2.82606 |
Sterimol/B4: 9.77514 | Sterimol/L: 17.3332 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 608.327 | Positive charged surface: 273.396 | Negative charged surface: 334.932 | Volume: 327 |
Hydrophobic surface: 476.812 | Hydrophilic surface: 131.515 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |