Physical Properties | | | |
Molecular Weight: 408.893 g/mol | logS: -7.11512 | SlogP: 5.48854 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0415957 | Sterimol/B1: 3.3096 | Sterimol/B2: 4.00155 | Sterimol/B3: 4.35575 |
Sterimol/B4: 8.28325 | Sterimol/L: 17.9514 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 678.718 | Positive charged surface: 455.237 | Negative charged surface: 217.51 | Volume: 380.375 |
Hydrophobic surface: 605.064 | Hydrophilic surface: 73.654 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |