Physical Properties | | | |
Molecular Weight: 387.891 g/mol | logS: -6.73256 | SlogP: 4.2608 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.00285052 | Sterimol/B1: 2.37518 | Sterimol/B2: 2.37635 | Sterimol/B3: 3.87306 |
Sterimol/B4: 4.81508 | Sterimol/L: 24.0967 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 675.672 | Positive charged surface: 386.149 | Negative charged surface: 289.523 | Volume: 353.625 |
Hydrophobic surface: 541.221 | Hydrophilic surface: 134.451 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |