Physical Properties | | | |
Molecular Weight: 399.466 g/mol | logS: -3.7587 | SlogP: 3.0394 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.189458 | Sterimol/B1: 2.52201 | Sterimol/B2: 3.22596 | Sterimol/B3: 5.2005 |
Sterimol/B4: 13.0252 | Sterimol/L: 14.9939 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 672.157 | Positive charged surface: 454.307 | Negative charged surface: 217.85 | Volume: 376.75 |
Hydrophobic surface: 540.963 | Hydrophilic surface: 131.194 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |