Physical Properties | | | |
Molecular Weight: 408.434 g/mol | logS: -5.78604 | SlogP: 3.5936 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0555143 | Sterimol/B1: 1.969 | Sterimol/B2: 3.3395 | Sterimol/B3: 4.46109 |
Sterimol/B4: 10.7868 | Sterimol/L: 16.5503 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 655.106 | Positive charged surface: 364.852 | Negative charged surface: 285.04 | Volume: 357 |
Hydrophobic surface: 520.022 | Hydrophilic surface: 135.084 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |