Physical Properties | | | |
Molecular Weight: 371.549 g/mol | logS: -4.17854 | SlogP: 3.64912 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0716833 | Sterimol/B1: 2.50744 | Sterimol/B2: 3.54376 | Sterimol/B3: 4.07463 |
Sterimol/B4: 7.85973 | Sterimol/L: 19.2166 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 648.327 | Positive charged surface: 420.027 | Negative charged surface: 228.3 | Volume: 375.125 |
Hydrophobic surface: 579.976 | Hydrophilic surface: 68.351 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |