Physical Properties | | | |
Molecular Weight: 409.394 g/mol | logS: -6.26109 | SlogP: 4.3881 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0265426 | Sterimol/B1: 2.76109 | Sterimol/B2: 3.07625 | Sterimol/B3: 4.4276 |
Sterimol/B4: 7.49164 | Sterimol/L: 23.0457 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 719.144 | Positive charged surface: 390.19 | Negative charged surface: 328.954 | Volume: 374.125 |
Hydrophobic surface: 581.346 | Hydrophilic surface: 137.798 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |