Physical Properties | | | |
Molecular Weight: 402.583 g/mol | logS: -3.87026 | SlogP: 2.4591 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.143959 | Sterimol/B1: 2.30661 | Sterimol/B2: 4.30478 | Sterimol/B3: 4.60083 |
Sterimol/B4: 9.81705 | Sterimol/L: 16.2665 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 682.133 | Positive charged surface: 495.574 | Negative charged surface: 186.559 | Volume: 413.75 |
Hydrophobic surface: 599.492 | Hydrophilic surface: 82.641 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |