Physical Properties | | | |
Molecular Weight: 415.602 g/mol | logS: -4.09642 | SlogP: 4.2663 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.14824 | Sterimol/B1: 2.59167 | Sterimol/B2: 5.17442 | Sterimol/B3: 6.72457 |
Sterimol/B4: 7.48256 | Sterimol/L: 17.0188 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 689.297 | Positive charged surface: 467.25 | Negative charged surface: 222.046 | Volume: 420.25 |
Hydrophobic surface: 585.224 | Hydrophilic surface: 104.073 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |