Physical Properties | | | |
Molecular Weight: 381.496 g/mol | logS: -4.42628 | SlogP: 4.10112 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.203997 | Sterimol/B1: 3.167 | Sterimol/B2: 4.44402 | Sterimol/B3: 5.27828 |
Sterimol/B4: 8.05055 | Sterimol/L: 16.2574 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 646.653 | Positive charged surface: 486.462 | Negative charged surface: 160.19 | Volume: 384.875 |
Hydrophobic surface: 583.874 | Hydrophilic surface: 62.779 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 2 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |