Physical Properties | | | |
Molecular Weight: 411.57 g/mol | logS: -5.72716 | SlogP: 4.61731 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0969184 | Sterimol/B1: 2.1721 | Sterimol/B2: 2.81815 | Sterimol/B3: 4.60415 |
Sterimol/B4: 10.9634 | Sterimol/L: 16.6137 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 692.48 | Positive charged surface: 487.494 | Negative charged surface: 200.489 | Volume: 412.625 |
Hydrophobic surface: 588.933 | Hydrophilic surface: 103.547 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |