Physical Properties | | | |
Molecular Weight: 497.518 g/mol | logS: -7.29698 | SlogP: 4.2683 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.137347 | Sterimol/B1: 1.97121 | Sterimol/B2: 3.96286 | Sterimol/B3: 4.85611 |
Sterimol/B4: 11.1462 | Sterimol/L: 14.8773 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 719.32 | Positive charged surface: 333.623 | Negative charged surface: 385.698 | Volume: 399.75 |
Hydrophobic surface: 427.893 | Hydrophilic surface: 291.427 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |