Physical Properties | | | |
Molecular Weight: 357.494 g/mol | logS: -4.85128 | SlogP: 4.1787 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0505596 | Sterimol/B1: 2.17174 | Sterimol/B2: 3.55589 | Sterimol/B3: 5.37961 |
Sterimol/B4: 7.00468 | Sterimol/L: 19.5007 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 675.303 | Positive charged surface: 458.415 | Negative charged surface: 216.887 | Volume: 377.75 |
Hydrophobic surface: 553.349 | Hydrophilic surface: 121.954 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |