Physical Properties | | | |
Molecular Weight: 384.409 g/mol | logS: -1.52314 | SlogP: 0.1555 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0946653 | Sterimol/B1: 2.36862 | Sterimol/B2: 4.2607 | Sterimol/B3: 4.87037 |
Sterimol/B4: 5.84144 | Sterimol/L: 18.524 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 600.407 | Positive charged surface: 410.538 | Negative charged surface: 189.869 | Volume: 323.25 |
Hydrophobic surface: 397.706 | Hydrophilic surface: 202.701 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |