Physical Properties | | | |
Molecular Weight: 418.517 g/mol | logS: -7.45827 | SlogP: 6.1001 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0139541 | Sterimol/B1: 2.57214 | Sterimol/B2: 4.19219 | Sterimol/B3: 4.82301 |
Sterimol/B4: 6.75585 | Sterimol/L: 24.052 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 728.095 | Positive charged surface: 437.341 | Negative charged surface: 290.754 | Volume: 395.125 |
Hydrophobic surface: 603.564 | Hydrophilic surface: 124.531 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |