Physical Properties | | | |
Molecular Weight: 385.444 g/mol | logS: -5.18757 | SlogP: 3.51436 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0265456 | Sterimol/B1: 3.27488 | Sterimol/B2: 3.40736 | Sterimol/B3: 3.66856 |
Sterimol/B4: 5.50571 | Sterimol/L: 19.7445 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 633.883 | Positive charged surface: 356.833 | Negative charged surface: 277.049 | Volume: 345.75 |
Hydrophobic surface: 448.184 | Hydrophilic surface: 185.699 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |