Physical Properties | | | |
Molecular Weight: 351.345 g/mol | logS: -3.47726 | SlogP: 2.2303 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.17395 | Sterimol/B1: 2.27601 | Sterimol/B2: 3.01602 | Sterimol/B3: 4.76487 |
Sterimol/B4: 9.35583 | Sterimol/L: 14.9975 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 563.056 | Positive charged surface: 282.861 | Negative charged surface: 246.571 | Volume: 307 |
Hydrophobic surface: 444.949 | Hydrophilic surface: 118.107 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |