Physical Properties | | | |
Molecular Weight: 395.418 g/mol | logS: -4.81378 | SlogP: 3.19787 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0431318 | Sterimol/B1: 3.64499 | Sterimol/B2: 3.84926 | Sterimol/B3: 4.60359 |
Sterimol/B4: 8.34173 | Sterimol/L: 21.0312 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 731.428 | Positive charged surface: 494.769 | Negative charged surface: 236.659 | Volume: 411.375 |
Hydrophobic surface: 640.958 | Hydrophilic surface: 90.47 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 0 | Acid groups: 0 | Basic groups: 2 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |