Physical Properties | | | |
Molecular Weight: 381.004 g/mol | logS: -3.72467 | SlogP: 4.63527 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0886485 | Sterimol/B1: 2.52528 | Sterimol/B2: 2.83082 | Sterimol/B3: 5.79554 |
Sterimol/B4: 8.18662 | Sterimol/L: 19.47 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 681.268 | Positive charged surface: 514.687 | Negative charged surface: 166.581 | Volume: 401.75 |
Hydrophobic surface: 619.412 | Hydrophilic surface: 61.856 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |