Physical Properties | | | |
Molecular Weight: 380.532 g/mol | logS: -3.25626 | SlogP: 5.08487 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0452047 | Sterimol/B1: 2.45327 | Sterimol/B2: 5.84529 | Sterimol/B3: 6.00658 |
Sterimol/B4: 6.07697 | Sterimol/L: 21.3075 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 732.784 | Positive charged surface: 530.943 | Negative charged surface: 201.841 | Volume: 402.5 |
Hydrophobic surface: 674.123 | Hydrophilic surface: 58.661 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |