Physical Properties | | | |
Molecular Weight: 385.871 g/mol | logS: -4.84106 | SlogP: 2.0151 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.101456 | Sterimol/B1: 2.3376 | Sterimol/B2: 4.78273 | Sterimol/B3: 5.4089 |
Sterimol/B4: 6.43665 | Sterimol/L: 18.1803 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 645.271 | Positive charged surface: 387.565 | Negative charged surface: 257.706 | Volume: 363.25 |
Hydrophobic surface: 513.203 | Hydrophilic surface: 132.068 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 0 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |