Physical Properties | | | |
Molecular Weight: 425.975 g/mol | logS: -6.86026 | SlogP: 7.2346 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.107201 | Sterimol/B1: 4.30859 | Sterimol/B2: 4.36717 | Sterimol/B3: 5.02113 |
Sterimol/B4: 8.38603 | Sterimol/L: 19.6245 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 760.961 | Positive charged surface: 424.675 | Negative charged surface: 336.287 | Volume: 425.625 |
Hydrophobic surface: 681.889 | Hydrophilic surface: 79.072 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |