Physical Properties | | | |
Molecular Weight: 392.907 g/mol | logS: -4.50421 | SlogP: 2.4973 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0786039 | Sterimol/B1: 2.49942 | Sterimol/B2: 4.32312 | Sterimol/B3: 4.77522 |
Sterimol/B4: 10.6489 | Sterimol/L: 16.9935 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 692.508 | Positive charged surface: 450.555 | Negative charged surface: 236.201 | Volume: 375.125 |
Hydrophobic surface: 536.942 | Hydrophilic surface: 155.566 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |