Physical Properties | | | |
Molecular Weight: 385.424 g/mol | logS: -3.99375 | SlogP: -0.48233 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.193215 | Sterimol/B1: 2.18518 | Sterimol/B2: 5.1568 | Sterimol/B3: 5.4816 |
Sterimol/B4: 7.16266 | Sterimol/L: 16.0851 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 613.862 | Positive charged surface: 353.411 | Negative charged surface: 256.815 | Volume: 343.375 |
Hydrophobic surface: 371.039 | Hydrophilic surface: 242.823 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |