Physical Properties | | | |
Molecular Weight: 374.437 g/mol | logS: -2.51847 | SlogP: 2.2169 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0878714 | Sterimol/B1: 2.81053 | Sterimol/B2: 3.87527 | Sterimol/B3: 5.08712 |
Sterimol/B4: 5.56889 | Sterimol/L: 17.6686 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 608.854 | Positive charged surface: 457.282 | Negative charged surface: 151.572 | Volume: 347.125 |
Hydrophobic surface: 454.968 | Hydrophilic surface: 153.886 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |