Physical Properties | | | |
Molecular Weight: 422.46 g/mol | logS: -3.75262 | SlogP: 2.90692 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.125262 | Sterimol/B1: 2.28941 | Sterimol/B2: 5.28322 | Sterimol/B3: 5.66909 |
Sterimol/B4: 6.75815 | Sterimol/L: 17.893 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 654.924 | Positive charged surface: 402.878 | Negative charged surface: 252.047 | Volume: 391.25 |
Hydrophobic surface: 551.273 | Hydrophilic surface: 103.651 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |