Physical Properties | | | |
Molecular Weight: 389.476 g/mol | logS: -4.88325 | SlogP: 5.5932 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.220681 | Sterimol/B1: 2.76127 | Sterimol/B2: 4.44173 | Sterimol/B3: 7.47779 |
Sterimol/B4: 9.43559 | Sterimol/L: 18.3023 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 745.177 | Positive charged surface: 504.011 | Negative charged surface: 241.165 | Volume: 407.25 |
Hydrophobic surface: 666.108 | Hydrophilic surface: 79.069 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |