Physical Properties | | | |
Molecular Weight: 398.394 g/mol | logS: -5.91631 | SlogP: 2.7719 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.122914 | Sterimol/B1: 2.52098 | Sterimol/B2: 3.38992 | Sterimol/B3: 4.50925 |
Sterimol/B4: 9.91223 | Sterimol/L: 17.2594 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 637.999 | Positive charged surface: 312.026 | Negative charged surface: 325.973 | Volume: 369.875 |
Hydrophobic surface: 454.109 | Hydrophilic surface: 183.89 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 2 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |