Physical Properties | | | |
Molecular Weight: 314.297 g/mol | logS: -4.58161 | SlogP: 2.68172 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0386246 | Sterimol/B1: 2.12431 | Sterimol/B2: 2.45025 | Sterimol/B3: 4.03187 |
Sterimol/B4: 6.75612 | Sterimol/L: 17.91 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 534.114 | Positive charged surface: 282.665 | Negative charged surface: 251.449 | Volume: 277.75 |
Hydrophobic surface: 407.169 | Hydrophilic surface: 126.945 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |