Physical Properties | | | |
Molecular Weight: 411.477 g/mol | logS: -3.70478 | SlogP: 2.9996 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.110895 | Sterimol/B1: 2.57203 | Sterimol/B2: 5.5664 | Sterimol/B3: 6.76144 |
Sterimol/B4: 7.04719 | Sterimol/L: 18.846 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 699.596 | Positive charged surface: 423.283 | Negative charged surface: 276.313 | Volume: 396.375 |
Hydrophobic surface: 552.912 | Hydrophilic surface: 146.684 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |