Physical Properties | | | |
Molecular Weight: 409.445 g/mol | logS: -7.06786 | SlogP: 4.72972 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0670618 | Sterimol/B1: 3.26112 | Sterimol/B2: 4.76224 | Sterimol/B3: 5.70778 |
Sterimol/B4: 8.48821 | Sterimol/L: 16.7898 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 669.501 | Positive charged surface: 415.208 | Negative charged surface: 254.293 | Volume: 384.75 |
Hydrophobic surface: 567.519 | Hydrophilic surface: 101.982 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |