Physical Properties | | | |
Molecular Weight: 321.417 g/mol | logS: -2.82297 | SlogP: 2.5137 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.111354 | Sterimol/B1: 3.05124 | Sterimol/B2: 4.2115 | Sterimol/B3: 4.50001 |
Sterimol/B4: 9.45592 | Sterimol/L: 15.9728 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 628.633 | Positive charged surface: 472.033 | Negative charged surface: 156.599 | Volume: 328.75 |
Hydrophobic surface: 556.305 | Hydrophilic surface: 72.328 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |