Physical Properties | | | |
Molecular Weight: 406.436 g/mol | logS: -5.77742 | SlogP: 4.68434 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.110391 | Sterimol/B1: 2.69346 | Sterimol/B2: 5.32455 | Sterimol/B3: 5.88043 |
Sterimol/B4: 6.49182 | Sterimol/L: 16.8182 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 651.846 | Positive charged surface: 366.067 | Negative charged surface: 285.779 | Volume: 367.875 |
Hydrophobic surface: 549.503 | Hydrophilic surface: 102.343 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |