Physical Properties | | | |
Molecular Weight: 393.378 g/mol | logS: -6.4485 | SlogP: 5.3472 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.215344 | Sterimol/B1: 2.5062 | Sterimol/B2: 3.19074 | Sterimol/B3: 5.13848 |
Sterimol/B4: 9.61742 | Sterimol/L: 15.6199 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 632.348 | Positive charged surface: 339.964 | Negative charged surface: 292.384 | Volume: 386.125 |
Hydrophobic surface: 543.231 | Hydrophilic surface: 89.117 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 1 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |