Physical Properties | | | |
Molecular Weight: 394.475 g/mol | logS: -4.5152 | SlogP: 3.4027 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0419967 | Sterimol/B1: 2.6422 | Sterimol/B2: 3.70195 | Sterimol/B3: 3.98871 |
Sterimol/B4: 10.4449 | Sterimol/L: 16.2326 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 700.958 | Positive charged surface: 540.72 | Negative charged surface: 160.237 | Volume: 386.625 |
Hydrophobic surface: 620.784 | Hydrophilic surface: 80.174 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |