Physical Properties | | | |
Molecular Weight: 374.469 g/mol | logS: -3.77406 | SlogP: 3.37884 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0765149 | Sterimol/B1: 2.40221 | Sterimol/B2: 2.58792 | Sterimol/B3: 5.48452 |
Sterimol/B4: 8.07654 | Sterimol/L: 17.3625 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 635.778 | Positive charged surface: 411.796 | Negative charged surface: 223.982 | Volume: 345.5 |
Hydrophobic surface: 526.66 | Hydrophilic surface: 109.118 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |