Physical Properties | | | |
Molecular Weight: 423.509 g/mol | logS: -4.92242 | SlogP: 4.29034 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0476935 | Sterimol/B1: 1.969 | Sterimol/B2: 3.25036 | Sterimol/B3: 4.77489 |
Sterimol/B4: 11.3548 | Sterimol/L: 18.2696 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 762.244 | Positive charged surface: 570.911 | Negative charged surface: 191.333 | Volume: 418.25 |
Hydrophobic surface: 648.608 | Hydrophilic surface: 113.636 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |