Physical Properties | | | |
Molecular Weight: 367.361 g/mol | logS: -3.82969 | SlogP: 1.48637 | Reactive groups: 0 |
| | | |
Topological Properties | | | |
Globularity: 0.0882766 | Sterimol/B1: 2.56156 | Sterimol/B2: 3.58087 | Sterimol/B3: 3.75217 |
Sterimol/B4: 9.00963 | Sterimol/L: 15.2707 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 604.293 | Positive charged surface: 338.353 | Negative charged surface: 265.939 | Volume: 328.125 |
Hydrophobic surface: 399.041 | Hydrophilic surface: 205.252 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |