Physical Properties | | | |
Molecular Weight: 319.357 g/mol | logS: -1.84621 | SlogP: 2.46937 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.420074 | Sterimol/B1: 3.60907 | Sterimol/B2: 6.00997 | Sterimol/B3: 6.0699 |
Sterimol/B4: 6.75984 | Sterimol/L: 12.0433 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 546.518 | Positive charged surface: 425.888 | Negative charged surface: 120.63 | Volume: 299 |
Hydrophobic surface: 445.513 | Hydrophilic surface: 101.005 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |