Physical Properties | | | |
Molecular Weight: 384.412 g/mol | logS: -6.30524 | SlogP: 2.7628 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0463656 | Sterimol/B1: 2.28256 | Sterimol/B2: 2.95543 | Sterimol/B3: 4.34377 |
Sterimol/B4: 9.35243 | Sterimol/L: 18.7237 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 629.995 | Positive charged surface: 389.596 | Negative charged surface: 240.4 | Volume: 336.5 |
Hydrophobic surface: 450.764 | Hydrophilic surface: 179.231 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |