Physical Properties | | | |
Molecular Weight: 409.482 g/mol | logS: -5.12249 | SlogP: 4.9288 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.0961464 | Sterimol/B1: 3.42264 | Sterimol/B2: 4.02035 | Sterimol/B3: 4.45248 |
Sterimol/B4: 8.26466 | Sterimol/L: 16.3344 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 658.797 | Positive charged surface: 457.928 | Negative charged surface: 200.869 | Volume: 394.375 |
Hydrophobic surface: 568.812 | Hydrophilic surface: 89.985 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |