Physical Properties | | | |
Molecular Weight: 395.839 g/mol | logS: -5.49656 | SlogP: 3.8726 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0341124 | Sterimol/B1: 2.59137 | Sterimol/B2: 3.38409 | Sterimol/B3: 4.34449 |
Sterimol/B4: 6.46177 | Sterimol/L: 21.0966 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 681.442 | Positive charged surface: 398.928 | Negative charged surface: 282.514 | Volume: 357.125 |
Hydrophobic surface: 483.545 | Hydrophilic surface: 197.897 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |