Physical Properties | | | |
Molecular Weight: 412.277 g/mol | logS: -4.44768 | SlogP: 3.3574 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.081143 | Sterimol/B1: 4.14681 | Sterimol/B2: 4.83098 | Sterimol/B3: 4.96322 |
Sterimol/B4: 5.8782 | Sterimol/L: 18.1376 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 649.643 | Positive charged surface: 403.688 | Negative charged surface: 245.955 | Volume: 353.375 |
Hydrophobic surface: 485.054 | Hydrophilic surface: 164.589 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |